Comparative killing rates of fluoroquinolones and cell wall-active agents.

نویسندگان

  • J C Fung-Tomc
  • E Gradelski
  • L Valera
  • B Kolek
  • D P Bonner
چکیده

Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and >/=6 h for streptococci and enterococci. Thus, the rate of killing by fluoroquinolones is organism group dependent; overall, they killed more rapidly than beta-lactams and vancomycin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 44 5  شماره 

صفحات  -

تاریخ انتشار 2000